Catharanthine tartrate
CAS No. 4168-17-6
Catharanthine tartrate( —— )
Catalog No. M18532 CAS No. 4168-17-6
Extracted from whole herb of Catharanthus roseus (L.)G.Don;Store the product in sealed, cool and dry condition.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 50MG | 343 | Get Quote |
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Biological Information
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Product NameCatharanthine tartrate
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NoteResearch use only, not for human use.
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Brief DescriptionExtracted from whole herb of Catharanthus roseus (L.)G.Don;Store the product in sealed, cool and dry condition.
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DescriptionExtracted from whole herb of Catharanthus roseus (L.)G.Don;Store the product in sealed, cool and dry condition.
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In Vitro——
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In VivoAnimal Model:13-week-old male SpragueDawley rats (300-350 g) Dosage:0.5-20 mg/kg Administration:IV; single dose Result:Evoked rapid, transient reductions in BP and HR (lasting ,2 minutes) at low doses (0.5–5 mg/kg), whereas at higher doses (10 and 20 mg/kg), the BP and HR reductions were sustained.
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetDHFR
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number4168-17-6
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Formula Weight486.51
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Molecular FormulaC25H30N2O8
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (205.55 mM)
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SMILES[C@]12(c3c(c4c([nH]3)cccc4)CCN3[C@@H]1C(=C[C@H](C2)C3)CC)C(=O)OC.C(C(C(=O)O)O)(C(=O)O)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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DS18561882
DS18561882 is an orally available, selective and potent inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) with antitumor activity, inhibits MTHFD1 activity and can be used in the study of breast cancer.
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Lometrexol
Lometrexol (LY 264618), an antipurine Antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks.
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Talotrexin ammonium
Talotrexin ammonium is a non-polyglutamic acid antifolate. Talotrexin ammonium inhibits tumor growth by targeting dihydrofolate reductase (DHFR), thereby improving anti-tumor activity in a wide range of cancer models, helping to inhibit tumor growth.
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